William E. Moerner, a pioneer in the field of singlemolecule spectroscopy, received the 2014 Nobel Prize in Chemistry for his work on developing ultrahigh-resolution microscopes capable of measuring single molecules at the nanoscale. Having earned three undergraduate degrees in physics, electrical engineering, and mathematics, Moerner explores the middle ground between theory and practice, maintaining a strong passion for interdisciplinary studies. On September 19, 2023, the Chey Institute invited him, along with Ha Taekjip (Professor, Harvard University) and Myong Sua (Professor, Harvard University), to discuss frontier technologies in molecular imaging and how they may reshape our understanding of life systems.